Application
TRIM23 Antibody (N-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the TRIM23 antibody detected the TRIM23 protein (arrow).Application
TRIM23 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human thyroid tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TRIM23 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | TRIM23 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TRIM23; ARD1; ARFD1; RNF46; E3 ubiquitin-protein ligase TRIM23; ADP-ribosylation factor domain-containing protein 1; GTP-binding protein ARD-1; RING finger protein 46; Tripartite motif-containing protein 23 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | ARD1 ARFD1 RNF46 |
|---|---|
| Alternative Names | TRIM23 ARD1 ARFD1 RNF46 E3 ubiquitin-protein ligase TRIM23 ADP-ribosylation factor domain-containing protein 1 GTP-binding protein ARD-1 RING finger protein 46 Tripartite motif-containing protein 23 |
| Molecular Weight(MW) | 64067 Da |
| Function | Acts as an E3 ubiquitin-protein ligase. In the presence of the human cytomegalovirus (HCMV) protein UL144, participates in 'Lys-63'-linked auto-ubiquitination of TRAF6 resulting in the virally controlled activation of NF-kappa-B at early time of infection. The C-terminus can act as an allosteric activator of the cholera toxin catalytic subunit |
| Tissue Specificity | This TRIM23 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 146-175 amino acids from the N-terminal region of human TRIM23. |
| Cellular Localization | Endomembrane system. Golgi apparatus membrane. Lysosome membrane. Note=Membrane-associated with the Golgi complex and lysosomal structures |
| Entrez Gene | 373 |
|---|---|
| Nucleotide Accession | NP_150230.1 NP_001647.1 NP_150231.1 |
Application
TRIM23 Antibody (N-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the TRIM23 antibody detected the TRIM23 protein (arrow).
Application
TRIM23 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human thyroid tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TRIM23 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
