Application
TRIM27 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the TRIM27 antibody detected the TRIM27 protein (arrow).| Product Name | TRIM27 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TRIM27; RFP; RNF76; Zinc finger protein RFP; RING finger protein 76; Ret finger protein; Tripartite motif-containing protein 27 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | RFP RNF76 |
|---|---|
| Alternative Names | TRIM27 RFP RNF76 Zinc finger protein RFP RING finger protein 76 Ret finger protein Tripartite motif-containing protein 27 |
| Molecular Weight(MW) | 58490 Da |
| Function | Has a transcriptional repressor activity by cooperating with EPC1. Induces apoptosis by activating Jun N-terminal kinase and p38 kinase and also increases caspase-3-like activity independently of mitochondrial events. May function in male germ cell development. Has DNA-binding activity and preferentially bound to double-stranded DNA (By similarity). E3 ubiquitin-protein ligase that mediates ubiquitination of PIK3C2B and inhibits its activity; mediates the formation of 'Lys-48'-linked polyubiquitin chains; the function inhibits CD4 T-cell activation |
| Tissue Specificity | Expressed in testis namely within the seminiferous tubules |
| Cellular Localization | Nucleus (By similarity). Cytoplasm (By similarity). Nucleus, PML body (By similarity). Note=Nuclear or cytoplasmic depending on the cell type (By similarity) Colocalized with PML and EIF3S6 in nuclear bodies |
| Entrez Gene | 5987 |
|---|---|
| Nucleotide Accession | NP_006501.1 |
Application
TRIM27 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the TRIM27 antibody detected the TRIM27 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
