Application
TRIM39 Antibody (Center) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the TRIM39 antibody detected the TRIM39 protein (arrow).Application
TRIM39 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TRIM39 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | TRIM39 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TRIM39; RNF23; TFP; E3 ubiquitin-protein ligase TRIM39; RING finger protein 23; Testis-abundant finger protein; Tripartite motif-containing protein 39 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | RNF23 TFP |
|---|---|
| Alternative Names | TRIM39 RNF23 TFP E3 ubiquitin-protein ligase TRIM39 RING finger protein 23 Testis-abundant finger protein Tripartite motif-containing protein 39 |
| Molecular Weight(MW) | 59690 Da |
| Function | E3 ubiquitin-protein ligase. May facilitate apoptosis by inhibiting APC/C-Cdh1-mediated poly-ubiquitination and subsequent proteasome-mediated degradation of the pro-apoptotic protein MOAP1 |
| Tissue Specificity | Ubiquitous; highly expressed in brain, heart, kidney, liver, skeletal muscle, spleen and testis |
| Cellular Localization | Cytoplasm, cytosol. Mitochondrion. Note=Found predominantly in the cytosol. Partial shift from the cytosol to the mitochondria when co-localized with MOAP1 |
| Entrez Gene | 56658 |
|---|---|
| Nucleotide Accession | NP_742013.1 NP_067076.2 |
Application
TRIM39 Antibody (Center) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the TRIM39 antibody detected the TRIM39 protein (arrow).
Application
TRIM39 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TRIM39 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
