Application
TRIP6 Antibody (N-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the TRIP6 antibody detected the TRIP6 protein (arrow).Application
TRIP6 Antibody (N-term) (AP14201a)immunohistochemistry analysis in formalin fixed and paraffin embedded human uterus tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TRIP6 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | TRIP6 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TRIP6; OIP1; Thyroid receptor-interacting protein 6; Opa-interacting protein 1; Zyxin-related protein 1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | OIP1 |
|---|---|
| Alternative Names | TRIP6 OIP1 Thyroid receptor-interacting protein 6 Opa-interacting protein 1 Zyxin-related protein 1 |
| Molecular Weight(MW) | 50288 Da |
| Function | Relays signals from the cell surface to the nucleus to weaken adherens junction and promote actin cytoskeleton reorganization and cell invasiveness. Involved in lysophosphatidic acid-induced cell adhesion and migration. Acts as a transcriptional coactivator for NF-kappa-B and JUN, and mediates the transrepression of these transcription factors induced by glucocorticoid receptor |
| Tissue Specificity | Abundantly expressed in kidney, liver and lung. Lower levels in heart, placenta and pancreas. Expressed in colonic epithelial cells. Up-regulated in colonic tumors |
| Cellular Localization | Cytoplasm, cytoskeleton. Cell junction, focal adhesion. Nucleus. Cytoplasm. Note=Shuttles between nucleus and cytoplasm |
| Entrez Gene | 7205 |
|---|---|
| Nucleotide Accession | NP_003293.2 |
Application
TRIP6 Antibody (N-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the TRIP6 antibody detected the TRIP6 protein (arrow).
Application
TRIP6 Antibody (N-term) (AP14201a)immunohistochemistry analysis in formalin fixed and paraffin embedded human uterus tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TRIP6 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
