Application
TRPC4AP Antibody (N-term) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the TRPC4AP antibody detected the TRPC4AP protein (arrow).| Product Name | TRPC4AP Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TRPC4AP; C20orf188; TRRP4AP; Short transient receptor potential channel 4-associated protein; Protein TAP1; TNF-receptor ubiquitous scaffolding/signaling protein |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | C20orf188 TRRP4AP |
|---|---|
| Alternative Names | TRPC4AP C20orf188 TRRP4AP Short transient receptor potential channel 4-associated protein Protein TAP1 TNF-receptor ubiquitous scaffolding/signaling protein |
| Molecular Weight(MW) | 90852 Da |
| Function | Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control The DCX(TRUSS) complex specifically mediates the polyubiquitination and subsequent degradation of MYC. Also participates in the activation of NFKB1 in response to ligation of TNFRSF1A, possibly by linking TNFRSF1A to the IKK signalosome Involved in JNK activation via its interaction with TRAF2. Also involved in elevation of endoplasmic reticulum Ca(2+) storage reduction in response to CHRM1 |
| Tissue Specificity | This TRPC4AP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 48-75 amino acids from the N-terminal region of human TRPC4AP. |
| Entrez Gene | 26133 |
|---|---|
| Nucleotide Accession | NP_056453.1 |
Application
TRPC4AP Antibody (N-term) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the TRPC4AP antibody detected the TRPC4AP protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
