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TRPM3 Antibody (N-term)

Catalog Number:OM223707
OM223707
Discount Price
OM223707-100ul
1~2 Week
100ul
OM223707-50ul
50ul
OM223707-20ul
20ul
1~2 Week
Product Profile
Product Name TRPM3 Antibody (N-term)
Antibody Type Primary Antibodies
Antigen Alias TRPM3; KIAA1616; LTRPC3; Transient receptor potential cation channel subfamily M member 3; Long transient receptor potential channel 3; Melastatin-2
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WBFC
WB:1:100~500 FC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms KIAA1616
LTRPC3
Alternative Names TRPM3
KIAA1616
LTRPC3
Transient receptor potential cation channel subfamily M member 3
Long transient receptor potential channel 3
Melastatin-2
Molecular Weight(MW) 197571 Da
Function Calcium channel mediating constitutive calcium ion entry. Its activity is increased by reduction in extracellular osmolarity, by store depletion and muscarinic receptor activation
Tissue Specificity Expressed primarily in the kidney and, at lower levels, in brain, testis, ovary, pancreas and spinal cord Expression in the brain and kidney was determined at protein level. In the kidney, expressed predominantly in the collecting tubular epithelium in the medulla, medullary rays, and periglomerular regions; in the brain, highest levels are found in the cerebellum, choroid plexus, the locus coeruleus, the posterior thalamus and the substantia nigra. Down-regulated in renal tumors compared to normal kidney
Cellular Localization Membrane; Multi-pass membrane protein.
Database Links
Entrez Gene 80036
Application

Application

Western blot analysis of TRPM3 Antibody (N-term) in MDA-MB435 cell line lysates (35ug/lane). TRPM3 (arrow) was detected using the purified Pab.

Application

TRPM3 Antibody (N-term) flow cytometric analysis of MDA-MB435 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Application Notes WB:1:100~500 FC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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