TRPV2 Antibody (N-term) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the TRPV2 antibody detected the TRPV2 protein (arrow).
TRPV2; VRL; Transient receptor potential cation channel subfamily V member 2; Osm-9-like TRP channel 2; Vanilloid receptor-like protein 1
Key Feature
Clonality
Polyclonal
Isotype
Ig
Host Species
Rabbit
Tested Applications
WB
WB:1:100~500
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
VRL
Alternative Names
TRPV2 VRL Transient receptor potential cation channel subfamily V member 2 Osm-9-like TRP channel 2 Vanilloid receptor-like protein 1
Molecular Weight(MW)
85981 Da
Function
Calcium-permeable, non-selective cation channel with an outward rectification. Seems to be regulated, at least in part, by IGF-I, PDGF and neuropeptide head activator. May transduce physical stimuli in mast cells. Activated by temperatures higher than 52 degrees Celsius; is not activated by vanilloids and acidic pH
Tissue Specificity
This TRPV2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-81 amino acids from the N-terminal region of human TRPV2.
Cellular Localization
Cell membrane; Multi-pass membrane protein (By similarity). Cytoplasm (By similarity). Melanosome Note=Translocates from the cytoplasm to the plasma membrane upon ligand stimulation (By similarity). Identified by mass spectrometry in melanosome fractions from stage I to stage IV
TRPV2 Antibody (N-term) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the TRPV2 antibody detected the TRPV2 protein (arrow).
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.