Application
TRPV5 Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the TRPV5 antibody detected the TRPV5 protein (arrow).| Product Name | TRPV5 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TRPV5; ECAC1; Transient receptor potential cation channel subfamily V member 5; Calcium transport protein 2; Epithelial calcium channel 1; Osm-9-like TRP channel 3 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | ECAC1 |
|---|---|
| Alternative Names | TRPV5 ECAC1 Transient receptor potential cation channel subfamily V member 5 Calcium transport protein 2 Epithelial calcium channel 1 Osm-9-like TRP channel 3 |
| Molecular Weight(MW) | 82551 Da |
| Function | Constitutively active calcium selective cation channel thought to be involved in Ca(2+) reabsorption in kidney and intestine. The channel is activated by low internal calcium level and the current exhibits an inward rectification. A Ca(2+)- dependent feedback regulation includes fast channel inactivation and slow current decay. Heteromeric assembly with TRPV6 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating (By similarity) |
| Tissue Specificity | Expressed at high levels in kidney, small intestine and pancreas, and at lower levels in testis, prostate, placenta, brain, colon and rectum |
| Cellular Localization | Apical cell membrane; Multi-pass membrane protein. Note=Colocalized with S100A10 and ANAX2 along the apical domain of kidney distal tubular cells (By similarity). The expression of the glycosylated form in the cell membrane is increased in the presence of WNK3 |
| Entrez Gene | 56302 |
|---|---|
| Nucleotide Accession | NP_062815.2 |
Application
TRPV5 Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the TRPV5 antibody detected the TRPV5 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
