TSPYL2 Antibody (Center) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the TSPYL2 antibody detected the TSPYL2 protein (arrow).
TSPYL2;CDA1; DENTT; TSPX; Testis-specific Y-encoded-like protein 2; Testis-specific Y-encoded-like protein 2; Cell division autoantigen 1; Testis-specific Y-encoded-like protein 2; Cutaneous T-cell lymphoma-associated antigen se20-4; Testis-specific Y-enco
Key Feature
Clonality
Polyclonal
Isotype
Ig
Host Species
Rabbit
Tested Applications
WB
WB:1:1000
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
CDA1 DENTT TSPX
Alternative Names
TSPYL2 CDA1 DENTT TSPX Testis-specific Y-encoded-like protein 2 Testis-specific Y-encoded-like protein 2 Cell division autoantigen 1 Testis-specific Y-encoded-like protein 2 Cutaneous T-cell lymphoma-associated antigen se20-4 Testis-specific Y-enco
Molecular Weight(MW)
79435 Da
Function
Part of the CASK/TRB1/TSPYL2 transcriptional complex which modulates gene expression in response to neuronal synaptic activity, probably by facilitating nucleosome assembly. May inhibit cell proliferation by inducing p53-dependent CDKN1A expression
Tissue Specificity
Ubiquitously expressed, with highest levels in brain, testis and heart, and lowest levels in liver and pancreas
Cellular Localization
Nucleus. Cytoplasm (By similarity). Note=Enriched in transcriptionally active regions of chromatin in neurons (By similarity)
TSPYL2 Antibody (Center) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the TSPYL2 antibody detected the TSPYL2 protein (arrow).
Application Notes
WB:1:1000
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.