Application
TTC5 Antibody (C-term) western blot analysis in U-937 cell line lysates (35ug/lane).This demonstrates the TTC5 antibody detected the TTC5 protein (arrow).| Product Name | TTC5 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TTC5;Tetratricopeptide repeat protein 5; Tetratricopeptide repeat protein 5; Stress-responsive activator of p300 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | TTC5 Tetratricopeptide repeat protein 5 Tetratricopeptide repeat protein 5 Stress-responsive activator of p300 |
|---|---|
| Molecular Weight(MW) | 48928 Da |
| Function | Adapter protein involved in p53/TP53 response that acts by regulating and mediating the assembly of multi-protein complexes. Required to facilitate the interaction between JMY and p300/EP300 and increase p53/TP53-dependent transcription and apoptosis. Prevents p53/TP53 degradation by MDM2 (By similarity) |
| Tissue Specificity | This TTC5 Antibody Antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 372-401 amino acids from the C-term region of human TTC5. |
| Cellular Localization | Nucleus. Cytoplasm. Note=Phosphorylation at Ser-203 results in nuclear localization, while unphosphorylated protein localizes to the cytoplasm (By similarity) |
| Entrez Gene | 91875 |
|---|
Application
TTC5 Antibody (C-term) western blot analysis in U-937 cell line lysates (35ug/lane).This demonstrates the TTC5 antibody detected the TTC5 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
