Application
TTF-1 Antibody (N-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the TTF-1 antibody detected the TTF-1 protein (arrow).| Product Name | TTF-1 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TTF1; Transcription termination factor 1; RNA polymerase I termination factor; Transcription termination factor I |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | TTF1 Transcription termination factor 1 RNA polymerase I termination factor Transcription termination factor I |
|---|---|
| Molecular Weight(MW) | 103051 Da |
| Function | Multifunctional nucleolar protein that terminates ribosomal gene transcription, mediates replication fork arrest and regulates RNA polymerase I transcription on chromatin. Plays a dual role in rDNA regulation, being involved in both activation and silencing of rDNA transcription. Interaction with BAZ2A/TIP5 recovers DNA-binding activity |
| Tissue Specificity | This TTF-1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 174-204 amino acids from the N-terminal region of human TTF-1. |
| Cellular Localization | Nucleus. Nucleus, nucleolus (By similarity). |
| Entrez Gene | 7270 |
|---|---|
| Nucleotide Accession | NP_031370.2 |
Application
TTF-1 Antibody (N-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the TTF-1 antibody detected the TTF-1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
