Application
TTLL8 Antibody (N-term) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the TTLL8 antibody detected the TTLL8 protein (arrow).| Product Name | TTLL8 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TTLL8; Protein monoglycylase TTLL8; Tubulin--tyrosine ligase-like protein 8 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | TTLL8 Protein monoglycylase TTLL8 Tubulin--tyrosine ligase-like protein 8 |
|---|---|
| Molecular Weight(MW) | 94676 Da |
| Function | Monoglycylase which modifies both tubulin and non- tubulin proteins, generating side chains of glycine on the gamma- carboxyl groups of specific glutamate residues of target proteins Monoglycylates tubulin, with a preference for alpha-tubulin toward beta-tubulin. Has the ability to modify non-tubulin proteins such as ANP32A, ANP32B, SET and NCL. Involved in the side-chain initiation step of the glycylation reaction by adding a single glycine chain to generate monoglycine side chains. Not involved in elongation step of the polyglycylation reaction (By similarity) |
| Tissue Specificity | This TTLL8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-67 amino acids from the N-terminal region of human TTLL8. |
| Cellular Localization | Cytoplasm, cytoskeleton (By similarity). Cell projection, cilium (By similarity). Cytoplasm, cytoskeleton, cilium axoneme (By similarity) |
Application
TTLL8 Antibody (N-term) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the TTLL8 antibody detected the TTLL8 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
