Application
TXNDC3 Antibody (Center) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the TXNDC3 antibody detected the TXNDC3 protein (arrow).Application
TXNDC3 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TXNDC3 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | TXNDC3 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | NME8; SPTRX2; TXNDC3; Thioredoxin domain-containing protein 3; NM23-H8; NME/NM23 family member 8; Spermatid-specific thioredoxin-2 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | SPTRX2 TXNDC3 |
|---|---|
| Alternative Names | NME8 SPTRX2 TXNDC3 Thioredoxin domain-containing protein 3 NM23-H8 NME/NM23 family member 8 Spermatid-specific thioredoxin-2 |
| Molecular Weight(MW) | 67270 Da |
| Function | Probably required during the final stages of sperm tail maturation in the testis and/or epididymis, where extensive disulfide bonding of fibrous sheath (FS) proteins occurs. May be involved in the reduction of disulfide bonds within the sperm FS components. In vitro, it has neither NDP kinase nor reducing activity on disulfide bonds |
| Tissue Specificity | Testis-specific. Expressed only in primary spermatocytes and round spermatids |
| Cellular Localization | Cytoplasm. |
| Entrez Gene | 51314 |
|---|---|
| Nucleotide Accession | NP_057700.3 |
Application
TXNDC3 Antibody (Center) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the TXNDC3 antibody detected the TXNDC3 protein (arrow).
Application
TXNDC3 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TXNDC3 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
