UBA6 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the UBA6 antibody detected the UBA6 protein (arrow).
UBA6; MOP4; UBE1L2; Ubiquitin-like modifier-activating enzyme 6; Monocyte protein 4; Ubiquitin-activating enzyme E1-like protein 2
Key Feature
Clonality
Polyclonal
Isotype
Ig
Host Species
Rabbit
Tested Applications
WB
WB:1:100~500
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
MOP4 UBE1L2
Alternative Names
UBA6 MOP4 UBE1L2 Ubiquitin-like modifier-activating enzyme 6 Monocyte protein 4 Ubiquitin-activating enzyme E1-like protein 2
Molecular Weight(MW)
117970 Da
Function
Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding an ubiquitin- E1 thioester and free AMP. Specific for ubiquitin, does not activate ubiquitin-like peptides. Differs from UBE1 in its specificity for substrate E2 charging. Does not charge cell cycle E2s, such as CDC34. Essential for embryonic development. Required for UBD/FAT10 conjugation. Isoform 2 may play a key role in ubiquitin system and may influence spermatogenesis and male fertility
Tissue Specificity
Widely expressed. Isoform 2 is predominantly expressed in testis with higher expression in adult testis than in fetal testis
UBA6 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the UBA6 antibody detected the UBA6 protein (arrow).
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.