Application
UBAC1 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the UBAC1 antibody detected the UBAC1 protein (arrow).Application
UBAC1 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the UBAC1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.Application
UBAC1 Antibody (C-term) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | UBAC1 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | UBAC1; GBDR1; KPC2; UBADC1; Ubiquitin-associated domain-containing protein 1; E3 ubiquitin-protein ligase subunit KPC2; Glialblastoma cell differentiation-related protein 1; Kip1 ubiquitination-promoting complex protein 2 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHCFC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | GBDR1 KPC2 UBADC1 |
|---|---|
| Alternative Names | UBAC1 GBDR1 KPC2 UBADC1 Ubiquitin-associated domain-containing protein 1 E3 ubiquitin-protein ligase subunit KPC2 Glialblastoma cell differentiation-related protein 1 Kip1 ubiquitination-promoting complex protein 2 |
| Molecular Weight(MW) | 45338 Da |
| Function | Non-catalytic subunit of the KPC complex that acts as E3 ubiquitin-protein ligase. Required for poly-ubiquitination and proteasome-mediated degradation of CDKN1B during G1 phase of the cell cycle |
| Tissue Specificity | Ubiquitous. |
| Cellular Localization | Cytoplasm. |
| Entrez Gene | 10422 |
|---|---|
| Nucleotide Accession | NP_057256.2 |
Application
UBAC1 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the UBAC1 antibody detected the UBAC1 protein (arrow).
Application
UBAC1 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the UBAC1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Application
UBAC1 Antibody (C-term) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
