Application
Western blot analysis of anti-UBE2D1 Pab in mouse cerebellum tissue lysates (35ug/lane). UBE2D1 (arrow) was detected using the purified Pab.| Product Name | UBE2D1 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | UBE2D1; SFT; UBC5A; UBCH5; UBCH5A; Ubiquitin-conjugating enzyme E2 D1; Stimulator of Fe transport; UBC4/5 homolog; UbcH5; Ubiquitin carrier protein D1; Ubiquitin-conjugating enzyme E2(17)KB 1; Ubiquitin-conjugating enzyme E2-17 kDa 1; Ubiquitin-protein lig |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | SFT UBC5A UBCH5 UBCH5A |
|---|---|
| Alternative Names | UBE2D1 SFT UBC5A UBCH5 UBCH5A Ubiquitin-conjugating enzyme E2 D1 Stimulator of Fe transport UBC4/5 homolog UbcH5 Ubiquitin carrier protein D1 Ubiquitin-conjugating enzyme E2(17)KB 1 Ubiquitin-conjugating enzyme E2-17 kDa 1 Ubiquitin-protein lig |
| Molecular Weight(MW) | 16602 Da |
| Function | Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys- 48'-linked polyubiquitination. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP- induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and auto-ubiquitination of STUB1, TRAF6 and TRIM63/MURF1 Ubiquitinates STUB1-associated HSP90AB1 in vitro. Lacks inherent specificity for any particular lysine residue of ubiquitin Essential for viral activation of IRF3. Mediates polyubiquitination of CYP3A4 |
| Tissue Specificity | Ubiquitous. Up-regulated in livers of iron- overloaded patients with hereditary hemochromatosis |
| Cellular Localization | Cytoplasm. |
Application
Western blot analysis of anti-UBE2D1 Pab in mouse cerebellum tissue lysates (35ug/lane). UBE2D1 (arrow) was detected using the purified Pab.| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
