Application
UBE2D2 Antibody (C-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the UBE2D2 antibody detected the UBE2D2 protein (arrow).| Product Name | UBE2D2 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | UBE2D2; UBC4; UBC5B; UBCH4; UBCH5B; Ubiquitin-conjugating enzyme E2 D2; Ubiquitin carrier protein D2; Ubiquitin-conjugating enzyme E2(17)KB 2; Ubiquitin-conjugating enzyme E2-17 kDa 2; Ubiquitin-protein ligase D2 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | PUBC1 UBC4 UBC5B UBCH4 UBCH5B |
|---|---|
| Alternative Names | UBE2D2 UBC4 UBC5B UBCH4 UBCH5B Ubiquitin-conjugating enzyme E2 D2 Ubiquitin carrier protein D2 Ubiquitin-conjugating enzyme E2(17)KB 2 Ubiquitin-conjugating enzyme E2-17 kDa 2 Ubiquitin-protein ligase D2 |
| Molecular Weight(MW) | 16735 Da |
| Function | Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys- 48'-linked polyubiquitination. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP- induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and autoubiquitination of STUB1 and TRAF6. Involved in the signal-induced conjugation and subsequent degradation of NFKBIA, FBXW2-mediated GCM1 ubiquitination and degradation, MDM2-dependent degradation of p53/TP53 and the activation of MAVS in the mitochondria by DDX58/RIG-I in response to viral infection Essential for viral activation of IRF3 |
| Tissue Specificity | This UBE2D2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 111-140 amino acids from the C-terminal region of human UBE2D2. |
| Entrez Gene | 7322 |
|---|---|
| Nucleotide Accession | NP_003330.1 NP_862821.1 |
Application
UBE2D2 Antibody (C-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the UBE2D2 antibody detected the UBE2D2 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
