Application
UBE2L3 Antibody (C-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the UBE2L3 antibody detected the UBE2L3 protein (arrow).| Product Name | UBE2L3 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | UBE2L3; UBCE7; UBCH7; Ubiquitin-conjugating enzyme E2 L3; L-UBC; UbcH7; Ubiquitin carrier protein L3; Ubiquitin-conjugating enzyme E2-F1; Ubiquitin-protein ligase L3 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | UBCE7 UBCH7 |
|---|---|
| Alternative Names | UBE2L3 UBCE7 UBCH7 Ubiquitin-conjugating enzyme E2 L3 L-UBC UbcH7 Ubiquitin carrier protein L3 Ubiquitin-conjugating enzyme E2-F1 Ubiquitin-protein ligase L3 |
| Molecular Weight(MW) | 17862 Da |
| Function | Ubiquitin-conjugating enzyme E2 that specifically acts with HECT-type and RBR family E3 ubiquitin-protein ligases. Does not function with most RING-containing E3 ubiquitin-protein ligases because it lacks intrinsic E3-independent reactivity with lysine: in contrast, it has activity with the RBR family E3 enzymes, such as PARK2 and ARIH1, that function like function like RING-HECT hybrids. Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'-linked polyubiquitination. Involved in the selective degradation of short-lived and abnormal proteins. Down- regulated during the S-phase it is involved in progression through the cell cycle. Regulates nuclear hormone receptors transcriptional activity. May play a role in myelopoiesis |
| Tissue Specificity | Ubiquitous, with highest expression in testis. |
| Cellular Localization | Nucleus. Cytoplasm. |
| Entrez Gene | 7332 |
|---|---|
| Nucleotide Accession | NP_003338.1 |
Application
UBE2L3 Antibody (C-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the UBE2L3 antibody detected the UBE2L3 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
