Western blot analysis of UBE2V antibody (C-term) (Cat.# AP2156b) in mouse brain tissue lysates (35ug/lane). UBE2V (arrow) was detected using the purified Pab.
Has no ubiquitin ligase activity on its own. The UBE2V2/UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly-ubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage
Tissue Specificity
Detected in placenta, colon, liver and skin. Detected at very low levels in most tissues
Western blot analysis of UBE2V antibody (C-term) (Cat.# AP2156b) in mouse brain tissue lysates (35ug/lane). UBE2V (arrow) was detected using the purified Pab.
Application Notes
WB:1:50~100
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.