Application
UBE3C Antibody (Center) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the UBE3C antibody detected the UBE3C protein (arrow).| Product Name | UBE3C Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | UBE3C;KIAA0010; KIAA10; Ubiquitin-protein ligase E3C; Ubiquitin-protein ligase E3C; HectH2 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:1000 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | KIAA0010 KIAA10 |
|---|---|
| Alternative Names | UBE3C KIAA0010 KIAA10 Ubiquitin-protein ligase E3C Ubiquitin-protein ligase E3C HectH2 |
| Molecular Weight(MW) | 123923 Da |
| Function | E3 ubiquitin-protein ligase that accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2D1 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Can assemble unanchored poly-ubiquitin chains in either 'Lys-29'- or 'Lys-48'-linked polyubiquitin chains. Has preference for 'Lys-48' linkages. It can target itself for ubiquitination in vitro and may promote its own degradation in vivo |
| Tissue Specificity | Highly expressed in skeletal muscle. Detected at much lower levels in kidney and pancreas |
| Cellular Localization | Nucleus (Potential). |
| Entrez Gene | 9690 |
|---|
Application
UBE3C Antibody (Center) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the UBE3C antibody detected the UBE3C protein (arrow).| Application Notes | WB:1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
