Application
UBXN1 Antibody (Center) western blot analysis in Ramos cell line lysates (35ug/lane).This demonstrates the UBXN1 antibody detected the UBXN1 protein (arrow).| Product Name | UBXN1 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | UBXN1; SAKS1; UBX domain-containing protein 1; SAPK substrate protein 1; UBA/UBX 33.3 kDa protein |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | SAKS1 |
|---|---|
| Alternative Names | UBXN1 SAKS1 UBX domain-containing protein 1 SAPK substrate protein 1 UBA/UBX 33.3 kDa protein |
| Molecular Weight(MW) | 33325 Da |
| Function | Ubiquitin-binding protein that interacts with the BRCA1- BARD1 heterodimer, and regulates its activity. Specifically binds 'Lys-6'-linked polyubiquitin chains. Interaction with autoubiquitinated BRCA1, leads to inhibit the E3 ubiquitin-protein ligase activity of the BRCA1-BARD1 heterodimer. Component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulum that are retrotranslocated in the cytosol |
| Tissue Specificity | This UBXN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 157-186 amino acids from the Central region of human UBXN1. |
| Cellular Localization | Cytoplasm (By similarity). |
| Entrez Gene | 51035 |
|---|---|
| Nucleotide Accession | NP_056937.2 |
Application
UBXN1 Antibody (Center) western blot analysis in Ramos cell line lysates (35ug/lane).This demonstrates the UBXN1 antibody detected the UBXN1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
