Application
UCHL5 Antibody (Center) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the UCHL5 antibody detected the UCHL5 protein (arrow).| Product Name | UCHL5 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | UCHL5; UCH37; Ubiquitin carboxyl-terminal hydrolase isozyme L5; Ubiquitin C-terminal hydrolase UCH37; Ubiquitin thioesterase L5 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | UCH37 |
|---|---|
| Alternative Names | UCHL5 UCH37 Ubiquitin carboxyl-terminal hydrolase isozyme L5 Ubiquitin C-terminal hydrolase UCH37 Ubiquitin thioesterase L5 |
| Molecular Weight(MW) | 37607 Da |
| Function | Protease that specifically cleaves 'Lys-48'-linked polyubiquitin chains. Deubiquitinating enzyme associated with the 19S regulatory subunit of the 26S proteasome. Putative regulatory component of the INO80 complex; however is inactive in the INO80 complex and is activated by a transient interaction of the INO80 complex with the proteasome via ADRM1 |
| Tissue Specificity | This UCHL5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 136-164 amino acids from the Central region of human UCHL5. |
| Cellular Localization | Cytoplasm. Nucleus. Note=Associates with the proteasome 19S subunit in the cytoplasm. Associates with the INO80 complex in the nucleus |
| Entrez Gene | 51377 |
|---|---|
| Nucleotide Accession | NP_057068.1 |
Application
UCHL5 Antibody (Center) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the UCHL5 antibody detected the UCHL5 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
