Application
UGT8 antibody (Center) western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the UGT8 antibody detected the UGT8 protein (arrow).Application
UGT8 antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of UGT8 antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | UGT8 antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | UGT8; CGT; UGT4; 2-hydroxyacylsphingosine 1-beta-galactosyltransferase; Ceramide UDP-galactosyltransferase; Cerebroside synthase; UDP-galactose-ceramide galactosyltransferase |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CGT UGT4 |
|---|---|
| Alternative Names | UGT8 CGT UGT4 2-hydroxyacylsphingosine 1-beta-galactosyltransferase Ceramide UDP-galactosyltransferase Cerebroside synthase UDP-galactose-ceramide galactosyltransferase |
| Molecular Weight(MW) | 61438 Da |
| Function | Catalyzes the transfer of galactose to ceramide, a key enzymatic step in the biosynthesis of galactocerebrosides, which are abundant sphingolipids of the myelin membrane of the central nervous system and peripheral nervous system |
| Tissue Specificity | This UGT8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 373-401 amino acids from the Central region of human UGT8. |
| Cellular Localization | Membrane; Single-pass membrane protein (Potential) |
| Entrez Gene | 7368 |
|---|---|
| Nucleotide Accession | NP_001121646.1 NP_003351.2 |
Application
UGT8 antibody (Center) western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the UGT8 antibody detected the UGT8 protein (arrow).
Application
UGT8 antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of UGT8 antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
