Application
ULBP3 Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the ULBP3 antibody detected the ULBP3 protein (arrow).| Product Name | ULBP3 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ULBP3; N2DL3; RAET1N; NKG2D ligand 3; ALCAN-gamma; Retinoic acid early transcript 1N |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | N2DL3 RAET1N |
|---|---|
| Alternative Names | ULBP3 N2DL3 RAET1N NKG2D ligand 3 ALCAN-gamma Retinoic acid early transcript 1N |
| Molecular Weight(MW) | 27949 Da |
| Function | Ligand for the NKG2D receptor, together with at least ULBP1 and ULBP2. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway. Has lower affinity for NKG2D compared to ULBP1 and ULBP2 and induces weaker signaling responses than does ULBP2 or ULBP1 |
| Tissue Specificity | This ULBP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 154-184 amino acids from the C-terminal region of human ULBP3. |
| Cellular Localization | Cell membrane; Lipid-anchor, GPI-anchor. |
| Entrez Gene | 79465 |
|---|---|
| Nucleotide Accession | NP_078794.1 |
Application
ULBP3 Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the ULBP3 antibody detected the ULBP3 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
