Application
Western blot analysis of UNC13B Antibody (Center) in 293 cell line lysates (35ug/lane). UNC13B (arrow) was detected using the purified Pab.Application
UNC13B Antibody (Center) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | UNC13B Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | UNC13B; UNC13; Protein unc-13 homolog B; Munc13-2 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBFC |
| WB:1:100~500 FC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | UNC13 |
|---|---|
| Alternative Names | UNC13B UNC13 Protein unc-13 homolog B Munc13-2 |
| Molecular Weight(MW) | 180679 Da |
| Function | Plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. Is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity- depending refilling of readily releasable vesicle pool (RRP) Essential for synaptic vesicle maturation in a subset of excitatory/glutamatergic but not inhibitory/GABA-mediated synapses (By similarity) |
| Tissue Specificity | Expressed in kidney cortical epithelial cells and brain |
| Cellular Localization | Cytoplasm (By similarity). Membrane; Peripheral membrane protein (By similarity). Cell membrane (By similarity). Cell junction, synapse (By similarity) Note=Localized to synapses. Translocated to the plasma membrane in response to phorbol ester binding (By similarity) |
| Entrez Gene | 10497 |
|---|
Application
Western blot analysis of UNC13B Antibody (Center) in 293 cell line lysates (35ug/lane). UNC13B (arrow) was detected using the purified Pab.
Application
UNC13B Antibody (Center) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 FC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
