Application
UNC5D Antibody (Center) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the UNC5D antibody detected the UNC5D protein (arrow).| Product Name | UNC5D Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | UNC5D; KIAA1777; UNC5H4; Netrin receptor UNC5D; Protein unc-5 homolog 4; Protein unc-5 homolog D |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | KIAA1777 UNC5H4 |
|---|---|
| Alternative Names | UNC5D KIAA1777 UNC5H4 Netrin receptor UNC5D Protein unc-5 homolog 4 Protein unc-5 homolog D |
| Molecular Weight(MW) | 105880 Da |
| Function | Receptor for netrin. May be involved in axon guidance by mediating axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand (By similarity) |
| Tissue Specificity | This UNC5D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 482-511 amino acids from the Central region of human UNC5D. |
| Cellular Localization | Membrane; Single-pass type I membrane protein (By similarity) |
| Entrez Gene | 137970 |
|---|---|
| Nucleotide Accession | NP_543148.2 |
Application
UNC5D Antibody (Center) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the UNC5D antibody detected the UNC5D protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
