Application
Western blot analysis of UPK1A Antibody (C-term) in K562 cell line lysates (35ug/lane). UPK1A (arrow) was detected using the purified Pab.| Product Name | UPK1A Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | UPK1A; TSPAN21; Uroplakin-1a; Tetraspanin-21; Uroplakin Ia |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | TSPAN21 |
|---|---|
| Alternative Names | UPK1A TSPAN21 Uroplakin-1a Tetraspanin-21 Uroplakin Ia |
| Molecular Weight(MW) | 28879 Da |
| Function | Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions (By similarity) |
| Tissue Specificity | High expression restricted to ureteric urothelium (most superficial cells); low expression in prostate Expression in normal urothelial cells is lost in culture. Some expression in tumor cell lines derived from urothelial malignancies |
| Cellular Localization | Membrane; Multi-pass membrane protein. |
| Entrez Gene | 11045 |
|---|
Application
Western blot analysis of UPK1A Antibody (C-term) in K562 cell line lysates (35ug/lane). UPK1A (arrow) was detected using the purified Pab.| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
