Application
URM1 antibody (Cat. #AM1883a) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the URM1 antibody detected the URM1 protein (arrow).| Product Name | URM1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | URM1; C9orf74; Ubiquitin-related modifier 1 homolog |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgM |
| Clone Number | 182CT27.2.2 |
| Host Species | Mouse |
| Tested Applications | WB |
| WB:1:100 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | C9orf74 |
|---|---|
| Alternative Names | URM1 C9orf74 Ubiquitin-related modifier 1 homolog |
| Molecular Weight(MW) | 11380 Da |
| Function | Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. May also act as an ubiquitin-like protein that is covalently conjugated to other proteins; the relevance of such function is however unclear in vivo |
| Tissue Specificity | This URM1 monoclonal antibody is generated from mouse immunized with URM1 recombinant protein. |
| Cellular Localization | Cytoplasm. |
| Entrez Gene | 81605 |
|---|
Application
URM1 antibody (Cat. #AM1883a) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the URM1 antibody detected the URM1 protein (arrow).| Application Notes | WB:1:100 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified monoclonal antibody supplied in saline solution with 0.09% (W/V) sodium azide. This antibody is prepared by Euglobin precipitation followed by dialysis against deionized water. |
