Application
USP1 Antibody (C-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the USP1 antibody detected the USP1 protein (arrow).| Product Name | USP1 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | USP1; Ubiquitin carboxyl-terminal hydrolase 1; Deubiquitinating enzyme 1; Ubiquitin thioesterase 1; Ubiquitin-specific-processing protease 1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | USP1 Ubiquitin carboxyl-terminal hydrolase 1 Deubiquitinating enzyme 1 Ubiquitin thioesterase 1 Ubiquitin-specific-processing protease 1 |
|---|---|
| Molecular Weight(MW) | 88207 Da |
| Function | Negative regulator of DNA damage repair which specifically deubiquitinates monoubiquitinated FANCD2. Also involved in PCNA-mediated translesion synthesis (TLS) by deubiquitinating monoubiquitinated PCNA. Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity |
| Tissue Specificity | This USP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 661-690 amino acids from the C-terminal region of human USP1. |
| Cellular Localization | Nucleus. |
| Entrez Gene | 7398 |
|---|---|
| Nucleotide Accession | NP_001017416.1 NP_001017415.1 |
Application
USP1 Antibody (C-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the USP1 antibody detected the USP1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
