Application
USH1C Antibody (N-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the USH1C antibody detected the USH1C protein (arrow).Application
USH1C Antibody (N-term) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the USH1C antibody detected the USH1C protein (arrow).| Product Name | USH1C (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | USH1C; AIE75; Harmonin; Antigen NY-CO-38/NY-CO-37; Autoimmune enteropathy-related antigen AIE-75; Protein PDZ-73; Renal carcinoma antigen NY-REN-3; Usher syndrome type-1C protein |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | AIE75 |
|---|---|
| Alternative Names | USH1C AIE75 Harmonin Antigen NY-CO-38/NY-CO-37 Autoimmune enteropathy-related antigen AIE-75 Protein PDZ-73 Renal carcinoma antigen NY-REN-3 Usher syndrome type-1C protein |
| Molecular Weight(MW) | 62211 Da |
| Function | Required for normal development and maintenance of cochlear hair cell bundles. Anchoring/scaffolding protein that is a part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells Required for normal hearing (By similarity) |
| Tissue Specificity | Expressed in small intestine, colon, kidney, eye and weakly in pancreas. Expressed also in vestibule of the inner ear |
| Cellular Localization | Cytoplasm, cytosol. Cytoplasm, cytoskeleton. Note=Colocalizes with F-actin (By similarity). Detected at the tip of cochlear hair cell stereocilia |
| Entrez Gene | 10083 |
|---|---|
| Nucleotide Accession | NP_005700.2 |
Application
USH1C Antibody (N-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the USH1C antibody detected the USH1C protein (arrow).
Application
USH1C Antibody (N-term) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the USH1C antibody detected the USH1C protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
