Application
USP16 Antibody (N-term) western blot analysis in SK-BR-3 cell line lysates (35ug/lane).This demonstrates the USP16 antibody detected the USP16 protein (arrow).| Product Name | USP16 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | USP16 Ubiquitin carboxyl-terminal hydrolase 16 Deubiquitinating enzyme 16 Ubiquitin thioesterase 16 Ubiquitin-processing protease UBP-M Ubiquitin-specific-processing protease 16 |
|---|---|
| Molecular Weight(MW) | 93570 Da |
| Function | Specifically deubiquitinates histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A is a prerequisite for subsequent phosphorylation at 'Ser-10' of histone H3, and is required for chromosome segregation when cells enter into mitosis Regulates Hox gene expression via histone H2A deubiquitination Prefers nucleosomal substrates. Does not deubiquitinate histone H2B |
| Tissue Specificity | Present in all the tissues examined including fetal brain, lung, liver, kidney, and adult heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas |
| Cellular Localization | Nucleus (Probable). |
| Entrez Gene | 10600 |
|---|---|
| Nucleotide Accession | NP_001001992.1 NP_001027582.1 |
Application
USP16 Antibody (N-term) western blot analysis in SK-BR-3 cell line lysates (35ug/lane).This demonstrates the USP16 antibody detected the USP16 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
