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VAMP4 Antibody (Center)

Catalog Number:OM224419
OM224419
Discount Price
OM224419-100ul
1~2 Week
100ul
OM224419-50ul
50ul
OM224419-20ul
20ul
1~2 Week
Product Profile
Product Name VAMP4 Antibody (Center)
Antibody Type Primary Antibodies
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WBIHC
WB:1:100~500 IHC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Alternative Names VAMP4
Vesicle-associated membrane protein 4
Molecular Weight(MW) 16397 Da
Function Involved in the pathway that functions to remove an inhibitor (probably synaptotagmin-4) of calcium-triggered exocytosis during the maturation of secretory granules. May be a marker for this sorting pathway that is critical for remodeling the secretory response of granule
Tissue Specificity This VAMP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 23-53 amino acids from the Central region of human VAMP4.
Cellular Localization Golgi apparatus, trans-Golgi network membrane; Single-pass type IV membrane protein (Probable) Note=Associated with trans Golgi network (TGN) and newly formed immature secretory granules (ISG). Not found on the mature secretory organelles
Database Links
Entrez Gene 8674
Nucleotide Accession NP_001172056.1 NP_003753.2
Application

Application

VAMP4 Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the VAMP4 antibody detected the VAMP4 protein (arrow).

Application

VAMP4 Antibody (Center) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the VAMP4 antibody detected the VAMP4 protein (arrow).

Application

VAMP4 antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the VAMP4 antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Application Notes WB:1:100~500 IHC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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