Application
VLDLR Antibody (Center) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the VLDLR antibody detected the VLDLR protein (arrow).Application
VLDLR Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the VLDLR Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.Application
VLDLR Antibody (Center) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | VLDLR Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | VLDLR; Very low-density lipoprotein receptor |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHCFC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | VLDLR Very low-density lipoprotein receptor |
|---|---|
| Molecular Weight(MW) | 96098 Da |
| Function | Binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. Binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation (By similarity) |
| Tissue Specificity | Abundant in heart and skeletal muscle; also ovary and kidney; not in liver |
| Cellular Localization | Membrane; Single-pass type I membrane protein. Membrane, clathrin-coated pit; Single-pass type I membrane protein |
| Entrez Gene | 7436 |
|---|---|
| Nucleotide Accession | NP_003374.3 |
Application
VLDLR Antibody (Center) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the VLDLR antibody detected the VLDLR protein (arrow).
Application
VLDLR Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the VLDLR Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Application
VLDLR Antibody (Center) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
