Application
VSX1 Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the VSX1 antibody detected the VSX1 protein (arrow).| Product Name | VSX1 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | VSX1; RINX; Visual system homeobox 1; Homeodomain protein RINX; Retinal inner nuclear layer homeobox protein; Transcription factor VSX1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | RINX |
|---|---|
| Alternative Names | VSX1 RINX Visual system homeobox 1 Homeodomain protein RINX Retinal inner nuclear layer homeobox protein Transcription factor VSX1 |
| Molecular Weight(MW) | 38431 Da |
| Function | Binds to the 37-bp core of the locus control region (LCR) of the red/green visual pigment gene cluster. May regulate the activity of the LCR and the cone opsin genes at earlier stages of development |
| Tissue Specificity | In the adult eye, expressed in lens, iris, ciliary body, choroid, optical nerve head and, most strongly, in retina, but not expressed in sclera and cornea. According to PubMed 11978762, expressed in adult retina but not in lens and cornea. Within adult retina, found exclusively in the inner nuclear layer. Isoform 1, isoform 2, isoform 3 and isoform 4 expressed in adult retina, but not in brain, heart, kidney, liver, lung, pancreas, placenta and skeletal muscle. Not expressed in thymus and spleen. Expressed in embryonic craniofacial tissue Expressed in fetal (week 14) retina. Strongly expressed in neonatal retina (day 0), weakly in neonatal lens (day 0), choroid (day 0) and cornea (day 0, 4; month 9) |
| Cellular Localization | Nucleus (By similarity). |
| Entrez Gene | 30813 |
|---|---|
| Nucleotide Accession | NP_055403.2 NP_955457.1 |
Application
VSX1 Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the VSX1 antibody detected the VSX1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
