Application
Western blot analysis of VTA1 Antibody (Center) in K562 cell line lysates (35ug/lane). VTA1 (arrow) was detected using the purified Pab.Application
Western blot analysis of VTA1 Antibody (Center) in NIH-3T3 cell line lysates (35ug/lane). VTA1 (arrow) was detected using the purified Pab;| Product Name | VTA1 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | VTA1; C6orf55; Vacuolar protein sorting-associated protein VTA1 homolog; Dopamine-responsive gene 1 protein; LYST-interacting protein 5; SKD1-binding protein 1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | C6orf55 |
|---|---|
| Alternative Names | VTA1 C6orf55 Vacuolar protein sorting-associated protein VTA1 homolog Dopamine-responsive gene 1 protein LYST-interacting protein 5 SKD1-binding protein 1 |
| Molecular Weight(MW) | 33879 Da |
| Function | Involved in the endosomal multivesicular bodies (MVB) pathway. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. Thought to be a cofactor of VPS4A/B, which catalyzes disassembles membrane-associated ESCRT-III assemblies. Involved in the sorting and down-regulation of EGFR (By similarity). Involved in HIV-1 budding |
| Tissue Specificity | This VTA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 159~189 amino acids from the Central region of human VTA1. |
| Cellular Localization | Cytoplasm. Endosome membrane; Peripheral membrane protein (Probable) |
| Entrez Gene | 51534 |
|---|
Application
Western blot analysis of VTA1 Antibody (Center) in K562 cell line lysates (35ug/lane). VTA1 (arrow) was detected using the purified Pab.
Application
Western blot analysis of VTA1 Antibody (Center) in NIH-3T3 cell line lysates (35ug/lane). VTA1 (arrow) was detected using the purified Pab;| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
