Application
WASF1 Antibody (Center) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the WASF1 antibody detected the WASF1 protein (arrow).Application
WASF1 Antibody (Center) (AP14110c)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of WASF1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | WASF1 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | WASF1; KIAA0269; SCAR1; WAVE1; Wiskott-Aldrich syndrome protein family member 1; Protein WAVE-1; Verprolin homology domain-containing protein 1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | KIAA0269 SCAR1 WAVE1 |
|---|---|
| Alternative Names | WASF1 KIAA0269 SCAR1 WAVE1 Wiskott-Aldrich syndrome protein family member 1 Protein WAVE-1 Verprolin homology domain-containing protein 1 |
| Molecular Weight(MW) | 61652 Da |
| Function | Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex |
| Tissue Specificity | Highly expressed in brain. Lowly expressed in testis, ovary, colon, kidney, pancreas, thymus, small intestine and peripheral blood |
| Cellular Localization | Cytoplasm, cytoskeleton. Note=Dot-like pattern in the cytoplasm. Concentrated in Rac-regulated membrane- ruffling areas |
| Entrez Gene | 8936 |
|---|---|
| Nucleotide Accession | NP_001020105.1 NP_001020107.1 NP_003922.1 |
Application
WASF1 Antibody (Center) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the WASF1 antibody detected the WASF1 protein (arrow).
Application
WASF1 Antibody (Center) (AP14110c)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of WASF1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
