WASF2 Antibody (Center) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the WASF2 antibody detected the WASF2 protein (arrow).
WASF2; WAVE2; Wiskott-Aldrich syndrome protein family member 2; Protein WAVE-2; Verprolin homology domain-containing protein 2
Key Feature
Clonality
Polyclonal
Isotype
Ig
Host Species
Rabbit
Tested Applications
WB
WB:1:100~500
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
WAVE2
Alternative Names
WASF2 WAVE2 Wiskott-Aldrich syndrome protein family member 2 Protein WAVE-2 Verprolin homology domain-containing protein 2
Molecular Weight(MW)
54284 Da
Function
Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex
Tissue Specificity
Expressed in all tissues with strongest expression in placenta, lung, and peripheral blood leukocytes, but not in skeletal muscle
Cellular Localization
Cytoplasm, cytoskeleton (By similarity). Cell projection, lamellipodium (By similarity). Note=At the interface between the lamellipodial actin meshwork and the membrane (By similarity)
WASF2 Antibody (Center) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the WASF2 antibody detected the WASF2 protein (arrow).
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.