WDR68 Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the WDR68 antibody detected the WDR68 protein (arrow).
DCAF7; HAN11; WDR68; DDB1- and CUL4-associated factor 7; WD repeat-containing protein 68; WD repeat-containing protein An11 homolog
Key Feature
Clonality
Polyclonal
Isotype
Ig
Host Species
Rabbit
Tested Applications
WB
WB:1:100~500
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
HAN11 WDR68
Alternative Names
DCAF7 HAN11 WDR68 DDB1- and CUL4-associated factor 7 WD repeat-containing protein 68 WD repeat-containing protein An11 homolog
Molecular Weight(MW)
38926 Da
Function
Involved in craniofacial development. Acts upstream of the EDN1 pathway and is required for formation of the upper jaw equivalent, the palatoquadrate. The activity required for EDN1 pathway function differs between the first and second arches (By similarity). Associates with DIAPH1 and controls GLI1 transcriptional activity. Could be involved in normal and disease skin development. May function as a substrate receptor for CUL4- DDB1 E3 ubiquitin-protein ligase complex
Tissue Specificity
This WDR68 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 285-314 amino acids from the C-terminal region of human WDR68.
Cellular Localization
Cytoplasm. Nucleus. Note=Overexpression of DIAHP1 or active RHOA causes translocation from the nucleus to cytoplasm
WDR68 Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the WDR68 antibody detected the WDR68 protein (arrow).
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.