WIPI1 Antibody (Center) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the WIPI1 antibody detected the WIPI1 protein (arrow).
WIPI1; WIPI49; WD repeat domain phosphoinositide-interacting protein 1; Atg18 protein homolog; WD40 repeat protein interacting with phosphoinositides of 49 kDa
Key Feature
Clonality
Polyclonal
Isotype
Ig
Host Species
Rabbit
Tested Applications
WB
WB:1:100~500
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
WIPI49
Alternative Names
WIPI1 WIPI49 WD repeat domain phosphoinositide-interacting protein 1 Atg18 protein homolog WD40 repeat protein interacting with phosphoinositides of 49 kDa
Molecular Weight(MW)
48673 Da
Function
May play a role in autophagy. May regulate the trafficking of proteins involved in the mannose-6-phosphate receptor (MPR) recycling pathway
Tissue Specificity
Ubiquitously expressed. Highly expressed in skeletal muscle, heart, testis, pancreas and placenta. Highly expressed in G361, Sk-mel-28, Sk-mel-13, WM852 and WM451 cells Up-regulated in a variety of tumor tissues
Cellular Localization
Golgi apparatus, trans-Golgi network. Endosome. Cytoplasmic vesicle, clathrin-coated vesicle. Note=Trans elements of the Golgi and peripheral endosomes. Dynamically cycles through these compartments and is susceptible to conditions that modulate membrane flux. Enriched in clathrin-coated vesicles
WIPI1 Antibody (Center) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the WIPI1 antibody detected the WIPI1 protein (arrow).
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.