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WIPI2 Antibody (N-term)

Catalog Number:OM224721
OM224721
Discount Price
OM224721-100ul
1~2 Week
100ul
OM224721-50ul
50ul
OM224721-20ul
20ul
1~2 Week
Product Profile
Product Name WIPI2 Antibody (N-term)
Antibody Type Primary Antibodies
Antigen Alias WIPI2; WD repeat domain phosphoinositide-interacting protein 2; WIPI49-like protein 2
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WBIHC
WB:1:100~500 IHC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Alternative Names WIPI2
WD repeat domain phosphoinositide-interacting protein 2
WIPI49-like protein 2
Molecular Weight(MW) 49408 Da
Function Probable early component of the autophagy machinery being involved in formation of preautophagosomal structures and their maturation into mature phagosomes in response to PtdIns3P May bind PtdIns3P
Tissue Specificity Ubiquitously expressed (at protein level). Highly expressed in heart, skeletal muscle and pancreas Expression is down-regulated in pancreatic and in kidney tumors
Cellular Localization Preautophagosomal structure membrane; Peripheral membrane protein; Cytoplasmic side. Note=Enriched at preautophagosomal structure membranes in response to ptdIns3P
Database Links
Application

Application

WIPI2 Antibody (N-term) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the WIPI2 antibody detected the WIPI2 protein (arrow).

Application

WIPI2 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of WIPI2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Application Notes WB:1:100~500 IHC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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