Application
XBP1 Antibody (C-term) western blot analysis in mouse lung tissue lysates (35ug/lane).This demonstrates the XBP1 antibody detected the XBP1 protein (arrow).| Product Name | XBP1 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | XBP1; TREB5; XBP2; X-box-binding protein 1; Tax-responsive element-binding protein 5 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | TREB5 XBP2 |
|---|---|
| Alternative Names | XBP1 TREB5 XBP2 X-box-binding protein 1 Tax-responsive element-binding protein 5 |
| Molecular Weight(MW) | 28695 Da |
| Function | Transcription factor essential for hepatocyte growth, the differentiation of plasma cells, the immunoglobulin secretion, and the unfolded protein response (UPR). Acts during endoplasmic reticulum stress (ER) by activating unfolded protein response (UPR) target genes via direct binding to the UPR element (UPRE) Binds DNA preferably to the CRE-like element 5'- GATGACGTG[TG]N(3)[AT]T-3', and also to some TPA response elements (TRE). Binds to the HLA DR-alpha promoter. Binds to the Tax- responsive element (TRE) of HTLV-I |
| Tissue Specificity | This XBP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 224-252 amino acids from the C-terminal region of human XBP1. |
| Cellular Localization | Nucleus. |
| Entrez Gene | 7494 |
|---|---|
| Nucleotide Accession | NP_001073007.1 NP_005071.2 |
Application
XBP1 Antibody (C-term) western blot analysis in mouse lung tissue lysates (35ug/lane).This demonstrates the XBP1 antibody detected the XBP1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
