Application
Figure 1: Western blot analysis using XBP1 mouse mAb against XBP1-hIgGFc transfected HEK293 cell lysate.| Product Name | XBP1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | XBP2; TREB5; XBP1 |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 1C4 |
| Host Species | Mouse |
| Tested Applications | WB |
| WB:1:500 - 2000. |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | TREB5 XBP2 |
|---|---|
| Alternative Names | XBP2 TREB5 XBP1 |
| Molecular Weight(MW) | 28695 Da |
| Function | Transcription factor essential for hepatocyte growth, the differentiation of plasma cells, the immunoglobulin secretion, and the unfolded protein response (UPR). Acts during endoplasmic reticulum stress (ER) by activating unfolded protein response (UPR) target genes via direct binding to the UPR element (UPRE) Binds DNA preferably to the CRE-like element 5'- GATGACGTG[TG]N(3)[AT]T-3', and also to some TPA response elements (TRE). Binds to the HLA DR-alpha promoter. Binds to the Tax- responsive element (TRE) of HTLV-I |
| Tissue Specificity | Purified recombinant fragment of human XBP1 expressed in E. Coli. |
| Cellular Localization | Nucleus. |
| Entrez Gene | 7494 |
|---|---|
| Nucleotide Accession | NP_005071.2 |
Application
Figure 1: Western blot analysis using XBP1 mouse mAb against XBP1-hIgGFc transfected HEK293 cell lysate.| Application Notes | WB:1:500 - 2000. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified recombinant fragment of human XBP1 expressed in E. Coli. |
