Application
XRN2 Antibody (N-term) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the XRN2 antibody detected the XRN2 protein (arrow).| Product Name | XRN2 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | XRN2; 5'-3' exoribonuclease 2; DHM1-like protein |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | XRN2 5'-3' exoribonuclease 2 DHM1-like protein |
|---|---|
| Molecular Weight(MW) | 108582 Da |
| Function | Possesses 5'->3' exoribonuclease activity (By similarity). May promote the termination of transcription by RNA polymerase II. During transcription termination, cleavage at the polyadenylation site liberates a 5' fragment which is subsequently processed to form the mature mRNA and a 3' fragment which remains attached to the elongating polymerase. The processive degradation of this 3' fragment by this protein may promote termination of transcription |
| Tissue Specificity | Expressed in the spleen, thymus, prostate, testis, ovary, small intestine, colon, peripheral blood leukocytes, heart, brain, placenta, lung, liver, skeletal muscle, kidney, and pancreas. Isoform 2 is expressed predominantly in peripheral blood leukocytes |
| Cellular Localization | Nucleus, nucleolus. |
| Entrez Gene | 22803 |
|---|---|
| Nucleotide Accession | NP_036387.2 |
Application
XRN2 Antibody (N-term) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the XRN2 antibody detected the XRN2 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
