Application
Western blot analysis of YBX2 Antibody (Center) Pab pre-incubated without(lane 1) and with(lane 2) blocking peptide in mouse stomach tissue lysate. YBX2 Antibody (Center) (arrow) was detected using the purified Pab (1:60/250 dilution).| Product Name | YBX2 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | YBX2; CSDA3; MSY2; Y-box-binding protein 2; Contrin; DNA-binding protein C; Germ cell-specific Y-box-binding protein; MSY2 homolog |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CSDA3 MSY2 |
|---|---|
| Alternative Names | YBX2 CSDA3 MSY2 Y-box-binding protein 2 Contrin DNA-binding protein C Germ cell-specific Y-box-binding protein MSY2 homolog |
| Molecular Weight(MW) | 38518 Da |
| Function | Major constituent of messenger ribonucleoprotein particles (mRNPs). Involved in the regulation of the stability and/or translation of germ cell mRNAs. Binds to Y-box consensus promoter element. Binds to full length mRNA with high affinity in a sequence-independent manner. Binds to short RNA sequences containing the consensus site 5'-UCCAUCA-3' with low affinity and limited sequence specificity. Its binding with maternal mRNAs is necessary for its cytoplasmic retention. May mark specific mRNAs (those transcribed from Y-box promoters) in the nucleus for cytoplasmic storage, thereby linking transcription and mRNA storage/translational delay (By similarity) |
| Tissue Specificity | Expressed in oocytes and testicular germ cells in the stage of spermatogonia to spermatocyte. Also observed placental trophoblasts, as well as in vascular smooth muscle cells in the pulmonary artery, myocardium, and skeletal muscle Undetectable in epithelial cells in respiratory, gastrointestinal, and urogenital tracts. Up-regulated in various carcinomas and germ cell tumors (at protein level) |
| Cellular Localization | Cytoplasm. Nucleus. |
| Entrez Gene | 51087 |
|---|---|
| Nucleotide Accession | NP_057066.2 |
Application
Western blot analysis of YBX2 Antibody (Center) Pab pre-incubated without(lane 1) and with(lane 2) blocking peptide in mouse stomach tissue lysate. YBX2 Antibody (Center) (arrow) was detected using the purified Pab (1:60/250 dilution).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
