ZDHC7 Antibody (C-term) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the ZDHC7 antibody detected the ZDHC7 protein (arrow).
ZDHHC7 ZNF370 Palmitoyltransferase ZDHHC7 Zinc finger DHHC domain-containing protein 7 Zinc finger protein 370
Molecular Weight(MW)
35140 Da
Function
Palmitoyltransferase with broad specificity. Palmitoylates SNAP25 and DLG4/PSD95. May palmitoylate GABA receptors on their gamma subunit (GABRG1, GABRG2 and GABRG3) and thereby regulate their synaptic clustering and/or cell surface stability (By similarity). Palmitoylates sex steroid hormone receptors, including ESR1, PGR and AR, thereby regulating their targeting to the plasma membrane. This affects rapid intracellular signaling by sex hormones via ERK and AKT kinases and the generation of cAMP, but does not affect that mediated by their nuclear receptors
Tissue Specificity
This ZDHC7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 239-267 amino acids from the C-terminal region of human ZDHC7.
Cellular Localization
Membrane; Multi-pass membrane protein (Potential). Golgi apparatus
ZDHC7 Antibody (C-term) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the ZDHC7 antibody detected the ZDHC7 protein (arrow).
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.