Application
Western blot analysis of ZDHHC21 Antibody (N-term) in mouse liver tissue lysates (35ug/lane).ZDHHC21 (arrow) was detected using the purified Pab.Application
ZDHHC21 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ZDHHC21 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.Application
ZDHHC21 Antibody (N-term) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | ZDHHC21 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHCFC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | ZDHHC21 Palmitoyltransferase ZDHHC21 Zinc finger DHHC domain-containing protein 21 |
|---|---|
| Molecular Weight(MW) | 31385 Da |
| Function | Palmitoylates sex steroid hormone receptors, including ESR1, PGR and AR, thereby regulating their targeting to the plasma membrane. This affects rapid intracellular signaling by sex hormones via ERK and AKT kinases and the generation of cAMP, but does not affect that mediated by their nuclear receptor (By similarity) |
| Tissue Specificity | This ZDHHC21 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 68-98 amino acids from the N-terminal region of human ZDHHC21. |
| Cellular Localization | Membrane; Multi-pass membrane protein (Potential). Golgi apparatus (By similarity) |
| Entrez Gene | 340481 |
|---|
Application
Western blot analysis of ZDHHC21 Antibody (N-term) in mouse liver tissue lysates (35ug/lane).ZDHHC21 (arrow) was detected using the purified Pab.
Application
ZDHHC21 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ZDHHC21 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Application
ZDHHC21 Antibody (N-term) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
