Application
Western blot analysis of ZFP36 Antibody (Center) in WiDr cell line lysates (35ug/lane). ZFP36 (arrow) was detected using the purified Pab.| Product Name | ZFP36 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | G0S24, RNF162A, TIS11A, TTP |
|---|---|
| Alternative Names | ZFP36 G0S24 RNF162A TIS11A TTP Tristetraprolin G0/G1 switch regulatory protein 24 Growth factor-inducible nuclear protein NUP475 Protein TIS11A Zinc finger protein 36 homolog |
| Molecular Weight(MW) | 34003 Da |
| Function | mRNA-binding protein involved in post-transcriptional regulation of AU-rich element (ARE)-containing mRNAs. Acts by specifically binding ARE-containing mRNAs and promoting their degradation. Plays a key role in the post-transcriptional regulation of tumor necrosis factor (TNF) |
| Tissue Specificity | This ZFP36 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 122~151 amino acids from the Center region of human ZFP36. |
| Cellular Localization | Nucleus. Cytoplasm. Note=Localizes to stress granules upon energy starvation. phosphorylation by MAPKAPK2 promotes exclusion from stress granules |
| Entrez Gene | 7538 |
|---|
Application
Western blot analysis of ZFP36 Antibody (Center) in WiDr cell line lysates (35ug/lane). ZFP36 (arrow) was detected using the purified Pab.| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
