Application
ZFP57 Antibody (Center) western blot analysis in human placenta tissue lysates (35ug/lane).This demonstrates the ZFP57 antibody detected the ZFP57 protein (arrow).| Product Name | ZFP57 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | C6orf40, ZNF698 |
|---|---|
| Alternative Names | ZFP57 C6orf40 ZNF698 Zinc finger protein 57 homolog Zinc finger protein 698 |
| Molecular Weight(MW) | 51919 Da |
| Function | Transcription regulator required to maintain maternal and paternal gene imprinting, a process by which gene expression is restricted in a parent of origin-specific manner by epigenetic modification of genomic DNA and chromatin, including DNA methylation. Acts by controlling DNA methylation during the earliest multicellular stages of development at multiple imprinting control regions. Required for the establishment of maternal methylation imprints at SNRPN locus. Acts as a transcriptional repressor in Schwann cells |
| Tissue Specificity | This ZFP57 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 268-296 amino acids from the Central region of human ZFP57. |
| Cellular Localization | Nucleus (By similarity). Note=Binds various differentially methylated regions (DMR), including the SNRPN DMR (By similarity) |
| Entrez Gene | 346171 |
|---|---|
| Nucleotide Accession | NP_001103279.2 |
Application
ZFP57 Antibody (Center) western blot analysis in human placenta tissue lysates (35ug/lane).This demonstrates the ZFP57 antibody detected the ZFP57 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
