Application
ZFP91 Antibody (Center) western blot analysis in HepG2,293 cell line lysates (35ug/lane).This demonstrates the ZFP91 antibody detected the ZFP91 protein (arrow).| Product Name | ZFP91 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | ZNF757 |
|---|---|
| Alternative Names | ZFP91 ZNF757 E3 ubiquitin-protein ligase ZFP91 Zinc finger protein 757 Zinc finger protein 91 homolog |
| Molecular Weight(MW) | 63445 Da |
| Function | Atypical E3 ubiquitin-protein ligase that mediates 'Lys- 63'-linked ubiquitination of MAP3K14/NIK, leading to stabilize and activate MAP3K14/NIK. It thereby acts as an activator of the non- canonical NF-kappa-B2/NFKB2 pathway. May also play an important role in cell proliferation and/or anti-apoptosis |
| Tissue Specificity | Expressed ubiquitously, particularly at high level in testis. Isoform 2 is testis specific |
| Cellular Localization | Nucleus. |
| Entrez Gene | 80829 |
|---|---|
| Nucleotide Accession | NP_444251.1 |
Application
ZFP91 Antibody (Center) western blot analysis in HepG2,293 cell line lysates (35ug/lane).This demonstrates the ZFP91 antibody detected the ZFP91 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
