Application
ZFYVE28 Antibody (C-term) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the ZFYVE28 antibody detected the ZFYVE28 protein (arrow).Application
ZFYVE28 antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ZFYVE28 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | ZFYVE28 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | KIAA1643, LST2 |
|---|---|
| Alternative Names | ZFYVE28 KIAA1643 LST2 Lateral signaling target protein 2 homolog Zinc finger FYVE domain-containing protein 28 |
| Molecular Weight(MW) | 96490 Da |
| Function | Negative regulator of epidermal growth factor receptor (EGFR) signaling. Acts by promoting EGFR degradation in endosomes when not monoubiquitinated |
| Tissue Specificity | This ZFYVE28 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 611-642 amino acids from the C-terminal region of human ZFYVE28. |
| Cellular Localization | Cytoplasm, cytosol. Early endosome membrane. Note=Localizes to early endosome membrane in absence of Lys-87 monoubiquitination. Localizes to cytosol when monoubiquitinated |
| Entrez Gene | 57732 |
|---|---|
| Nucleotide Accession | NP_001166130.1 NP_066023.2 NP_001166131.1 NP_001166127.1 NP_001166129.1 |
Application
ZFYVE28 Antibody (C-term) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the ZFYVE28 antibody detected the ZFYVE28 protein (arrow).
Application
ZFYVE28 antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ZFYVE28 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
